Expression of Midkine and Vascular Endothelial Growth Factor in Bone Marrow of Patients with Multiple Myeloma and Its Significance 中期因子及血管内皮生长因子在多发性骨髓瘤患者骨髓中的表达及意义
Objective To study the curative effect and side effect of thalidomide incorporation with VAD in the treatment of multiple myeloma and the significance of the change of serum VEGF ( vascular endothelial growth factor) concentration in multiple myeloma. 目的探讨沙利度胺联合VAD方案治疗多发性骨髓瘤(multiplemyeloma,MM)的临床疗效及治疗前后血管内皮生长因子(VascularEndothelialGrowthFactor,VEGF)水平变化。
Objective To investigate the plasma concentrations of brain-derived neurotrophic factor ( BDNF) and vascular endothelial growth factor ( VEGF) in patients with multiple myeloma ( MM), and to explore their relationship with the pathogenesis of the disease. 目的了解血浆脑源性神经营养因子(BDNF)、血管内皮细胞生长因子(VEGF)在多发性骨髓瘤(MM)病人中的含量,并探讨其在MM发病中的作用。